INDICATIONS Clarithromycin 125 mg/5 ml suspension is indicated in adults, adolescents and children, 6 months to 12 years, for the treatment of the following acute and chronic infections, when caused by clarithromycin susceptible organisms. ?????? Infections of the upper respiratory tract such as tonsillitis/pharyngitis, as an alternative when beta lactam antibiotics are not appropriate. ?????? Acute otitis media in children. ?????? Infections of the lower respiratory tract such as community acquired pneumonia. ?????? Sinusitis and acute exacerbation of chronic bronchitis in adults and adolescents over 12 years of age ?????? Skin infections and soft tissue infections of mild to moderate severity. In appropriate combination with antibacterial therapeutic regimens and an appropriate ulcer healing medicinal product for the eradication of?????Helicobacter pylori?????in adult patients with?????H. pylori associated ulcers. Consideration should be given to official guidance on the appropriate use of antibacterial agents. DOSAGE Children 6 months to 12 years of age: The recommended dose is 7.5 mg/kg twice a day. Weight Age Dosage

8 ?????? 11 kg	1 ?????? 2 years	2.5 ml twice daily
12 ?????? 19 kg	2 ?????? 4 years	5.0 ml twice daily
20 ?????? 29 kg	4 ?????? 8 years	7.5 ml twice daily
30 ?????? 40 kg	8 ?????? 12 years	10.0 ml twice daily

  Children under 12 years of age should use clarithromycin pediatric suspension (granules for oral suspension). There is limited experience of treatment of children below 6 months of age. Adults and adolescents: Standard dosage: The usual dose is 250 mg twice daily. High dosage treatment (severe infections): The usual dose may be increased to 500 mg twice daily in severe infections. Elimination of Helicobacter pylori in adults: In patients with gastro-duodenal ulcers due to?????H. pylori?????infection clarithromycin as part of the first line triple therapy is given in a dosage of 500 mg twice daily. The national recommendations for?????Helicobacter pylori?????eradication have to be considered. Dosage in patients with renal impairment: The maximum recommended dosages should be reduced proportionately to renal impairment. At creatinine clearance rate of less than 30 ml/min, the dosage should be halved to 250 mg daily or in the most severe infections to 250 mg twice daily. The duration of treatment should not exceed 14 days in these patients. PREGNANCY AND LACTATION Incase of pregnancy or lactating mothers, consult a medical practitioner. SIDE EFFECTS Insomnia, Dysgeusia, headache, Vasodilation, Diarrhoea, vomiting, dyspepsia, nausea, abdominal pain, Rash. ACTIVE INGREDIENT clarithromycin